Detalhe da pesquisa
1.
The NIH Somatic Cell Genome Editing program.
Nature
; 592(7853): 195-204, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33828315
2.
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Nature
; 582(7813): 586-591, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32494005
3.
Harnessing the effects of hypoxia-like inhibition on homology-directed DNA repair.
Semin Cancer Biol
; 98: 11-18, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38029867
4.
Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation.
Nucleic Acids Res
; 50(10): e59, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235944
5.
An ELISA-based platform for rapid identification of structure-dependent nucleic acid-protein interactions detects novel DNA triplex interactors.
J Biol Chem
; 298(10): 102398, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988651
6.
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.
Mol Cell
; 55(1): 31-46, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882211
7.
Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation.
Oncologist
; 26(7): e1104-e1109, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742489
8.
Peptide nucleic acids and their role in gene regulation and editing.
Biopolymers
; 112(12): e23460, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34129732
9.
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
Nature
; 518(7537): 107-10, 2015 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409146
10.
Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery.
Int J Mol Sci
; 22(23)2021 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884568
11.
Impact of hypoxia on DNA repair and genome integrity.
Mutagenesis
; 35(1): 61-68, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282537
12.
Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules Using a pH-Low Insertion Peptide.
Mol Pharm
; 17(2): 461-471, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855437
13.
Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair.
Molecules
; 25(3)2020 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046275
14.
A cell-penetrating antibody inhibits human RAD51 via direct binding.
Nucleic Acids Res
; 45(20): 11782-11799, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29036688
15.
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.
Breast Cancer Res
; 20(1): 16, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510720
16.
Metastatic and multiply relapsed SDH-deficient GIST and paraganglioma displays clinical response to combined poly ADP-ribose polymerase inhibition and temozolomide.
Pediatr Blood Cancer
; 70(3): e30020, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151992
17.
Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing.
Molecules
; 23(3)2018 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534473
18.
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells.
Carcinogenesis
; 38(6): 627-637, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472268
19.
LKB1 preserves genome integrity by stimulating BRCA1 expression.
Nucleic Acids Res
; 43(1): 259-71, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488815
20.
Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.
Yale J Biol Med
; 90(4): 583-598, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29259523